Автор: Mark Rogge and David R. Taft Название: Preclinical Drug Development, 2nd Edition Издательство: CRC Press Год: 2009 ISBN: 9781420084726; 1420084720 Серия: Drugs and the Pharmaceutical Sciences (Book 187) Язык: English Формат: pdf Размер: 10,4 mb Страниц: 376
Topics range from assessment of pharmacology and toxicology to industry trends and regulatory expectations to requirements that support clinical trials. Highlights of the Second Edition include:
- Pharmacokinetics - Modeling and simulation - Formulation and routes of administration - Toxicity evaluations - The assessment of drug absorption and metabolism - Interspecies scaling - Lead molecule selection and optimization via profiling - Screening using in silico and in vitro toxicity evaluations
The book also includes case studies on preclinical pharmacokinetic-pharmacodynamic modeling and simulation in drug development, a review of ICH preclinical guidelines, and experimental methods used to study membrane drug transport and metabolism. This guide is a fundamental resource for medicinal chemists, biologists, and other specialists in the drug development sciences.
Handbook of Drug Metabolism, 2nd Edition Автор: Paul G. Pearson and Larry C. Wienkers Название: Handbook of Drug Metabolism, 2nd Edition Издательство: CRC Press Год: 2008 ISBN:...
Drug-Drug Interactions, 2nd Edition Автор: A. Rodrigues David Название: Drug-Drug Interactions, 2nd Edition Издательство: CRC Press Год: 2008 ISBN: 978-0849375934 Серия: Drugs and the...
Preclinical Drug Development Автор: Mark C. Rogge and David R. Taft Название: Preclinical Drug Development Издательство: CRC Press Год: 2005 ISBN: 9781574448825 Серия: Drugs and...
Навигация
Вход на сайт
Реклама
Preclinical Drug Development, 2nd Edition 
